开始啃 CNS

• 想看的论文自己收好

• Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy 癌细胞进入 drug-tolerant persister 来逃避化疗，作者发现前后并没有遗传瓶颈，就像胚胎“滞育”

• Transvection regulates the sex-biased expression of a fly X-linked gene 性二态一般是由sex determination 的遗传机制来控制，作者发现一个基因是通过其它机制控制的

• Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion | spike蛋白两次剪切，电镜研究分子机制

• There’s plenty of room at the Top: What will drive computer performance after Moore’s law?

• A system hierarchy for brain-inspired computing

• Information arms race explains plant-herbivore chemical communication in ecological communities

• The coupling mechanism of mammalian respiratory complex I

• Manipulating synthetic optogenetic odors reveals the coding logic of olfactory perception

• Resource conservation manifests in the genetic code

• Boltzmann generators: Sampling equilibrium states of many-body systems with deep learning 玻尔兹曼采样

• Genomic architecture of a genetically assimilated seasonal color pattern

• Cryo-EM with sub–1 Å specimen movement

可以看看 figure

• Local convergence of behavior across species 局部环境，在不同物种间选择相似的行为
• Functional adaptive landscapes predict terrestrial capacity at the origin of limbs 四足类登陆，完整化石太少，作者用 40 残肢化石。。发现 transitional..origin..adaptive
• 11 TOPS photonic convolutional accelerator for optical neural networks 光学？卷积网络

重点是问题而不是某篇文献

• 单细胞测序是如何产生生物学发现的
  • Decoding myofibroblast origins in human kidney fibrosis 单细胞测序，一堆分析，检测，肾纤维化。 用了多种方法，最后得到结果

感谢李程老师分享的一篇公众号文章——《如何高效地读完一周的 CNS？》¹。酝tuo酿了几天后，终于开始了。虽然很鄙视暴利的学术出版，很厌恶唯论文、唯影响因子，也经常戏称灌水CNS；但是以我现在的科研能力和学术视野，好好钻研一番肯定是利大于弊的。

还记得曾经尝试每周去图书馆看纸质版（护眼），但当时连文章类型都分不清楚，别说是摘要，到最后都只能够看标题了。

• https://science.sciencemag.org/#research-articles
• https://www.nature.com/nature/current-issue#Research
• https://www.sciencedirect.com/journal/cell/latest

附模板：

# Science - Research Articles
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# Science - Reports
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# Nature
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# Cell
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