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02周：Jan08 Science, Jan07 Nature, Jan07 Cell

Posted on 3 mins read

Science - Research Articles

  1. Coordination between microbiota and root endodermis supports plant mineral nutrient homeostasis 植物，根，内胚层，微生物，共处
  2. Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth 中和抗体与病毒胞膜蛋白共进化，HIV-1 Env 猕猴和人类的。。很像
  3. Tubulin glycylation controls axonemal dynein activity, flagellar beat, and male fertility 微管蛋白只在鞭毛和纤毛中才会糖基化，作者在小鼠中敲除糖基化蛋白，从而研究其功能
  4. Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2 Prp2 的原子结构：单独，结合 Spp2，。。。
  5. A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis 不发炎。没看懂为什么用抗原能治疗自身免疫
  6. Anterior cingulate inputs to nucleus accumbens control the social transfer of pain and analgesia 共情的神经回路
  7. Crossover from hydrogen to chemical bonding 实验测量，氢键从什么时候强到成为化合键

Science - Reports

  1. Carbonaceous chondrite meteorites experienced fluid flow within the past million years 地球水来自太空，多个假设，作者挑一个（母星还有冰）
  2. Lithium pollution of a white dwarf records the accretion of an extrasolar planetesimal 白矮星，重元素来源
  3. Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans 新冠在牧场，人传动物再传人
  4. Microbial sulfate reduction and organic sulfur formation in sinking marine particles 海洋缺氧区
  5. Pre–T cell receptors topologically sample self-ligands during thymocyte β-selection
  6. A ubiquitous tire rubber–derived chemical induces acute mortality in coho salmon 银鲑为什么会死？某化学物质
  7. A broadly protective antibody that targets the flavivirus NS1 protein 黄病毒广谱抗体
  8. Structural basis for antibody inhibition of flavivirus NS1–triggered endothelial dysfunction 三个晶体结构，揭示了上一篇文章的结构机制

Nature

  1. Competing magnetic orders in a bilayer Hubbard model with ultracold atoms 从二维到双层
  2. 11 TOPS photonic convolutional accelerator for optical neural networks 光学？卷积网络
  3. Parallel convolutional processing using an integrated photonic tensor core 硬件，光子 tensor 核，并行
  4. Origins of structural and electronic transitions in disordered silicon
  5. Single-defect phonons imaged by electron microscopy 单个晶体缺陷与光子的作用
  6. Poleward and weakened westerlies during Pliocene warmth 西风变弱
  7. Drivers and dynamics of a massive adaptive radiation in cichlid fishes 适应辐射
  8. Mobility network models of COVID-19 explain inequities and inform reopening 简单的模型就可以解释新冠传播
  9. Neuronal diversity and convergence in a visual system developmental atlas scRNA，果蝇神经系统
  10. Coupling of hippocampal theta and ripples with pontogeniculooccipital waves 海马。波
  11. TRF2-independent chromosome end protection during pluripotency TRF2 保护端粒，但胚胎干细胞有另一种机制
  12. TRF2-mediated telomere protection is dispensable in pluripotent stem cells 同上，，POT1B or BRD2 是另一机制的分子
  13. A network of transcriptional repressors modulates auxin responses 转录因子网络调控生长素受体
  14. Prokaryotic viperins produce diverse antiviral molecules 细胞用 Viperin 防病毒，早在细菌就已经用来防噬菌体了
  15. The coding capacity of SARS-CoV-2 ribosome-profiling，发现 23 新 ORF，新冠的 mRNA 不是靠翻译效率，而是靠数量取胜（超过人 mRNA）
  16. Commensal-driven immune zonation of the liver promotes host defence 肝脏调节免疫细胞的定位
  17. RNA nucleation by MSL2 induces selective X chromosome compartmentalization 剂量补偿，MSL2 定位到 X 染色体
  18. Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline 电镜，bedaquiline 如何抗菌
  19. Structure of the class D GPCR Ste2 dimer coupled to two G proteins GPCR 分六类，D 型只在真菌有，我来首次解结构

Cell

  1. Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity 25k 基因组，还是不能确定 D614G 被正向选择
  2. Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection
  3. Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells
  4. Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses
  5. Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks 四篇都是用 CRISPR 筛新冠的宿主 factor
  6. TMEM41B Is a Pan-flavivirus Host Factor 这次筛黄病毒
  7. Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes COVID-19 产生过多的细胞因子，作者发现的这条通路很有治疗意义
  8. Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19 感染后抗体持续三个月
  9. Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis 转录，形成 cap 的中间态
  10. Structural Basis of WLS/Evi-Mediated Wnt Transport and Secretion Wnt，结构生物学
  11. RNA-Mediated Feedback Control of Transcriptional Condensates 转录，condensate ，初期正反馈+后期负反馈
  12. Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy 癌细胞进入 drug-tolerant persister 来逃避化疗，作者发现前后并没有遗传瓶颈，就像胚胎“滞育”
  13. Cranial Suture Regeneration Mitigates Skull and Neurocognitive Defects in Craniosynostosis 某疾病的小鼠模型
  14. Top-Down Control of Sweet and Bitter Taste in the Mammalian Brain 甜味和苦味的神经通路