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03周:Jan15 Science, Jan14 Nature

Science - Research Articles

  1. Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer’s disease 三个酶都有“副业”,去鞘化。。。Alzheimer 突触丢失
  2. Transmission heterogeneities, kinetics, and controllability of SARS-CoV-2 湖南,80%的二次感染来自 15% 初次感染。。传播异质性。。
  3. Aberrant type 1 immunity drives susceptibility to mucosal fungal infections 1型免疫增强,而不是 17型免疫减弱。。对*真菌易感
  4. Controlled hydroxylations of diterpenoids allow for plant chemical defense without autotoxicity 二萜,羟基化。。化学防御和避免自毒可以兼得

Science - Reports

  1. Formation of α clusters in dilute neutron-rich matter 实验证明 α cluster的存在。。符合理论。。也需要修改,解释α 射线的来源
  2. Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders 衰老细胞的溶酶体破损,pH 降低,于是诱导 glutaminase,分解谷氨酰胺,产生氨来中和。。所以抑制这个酶可以去除衰老细胞
  3. GPER1 is required to protect fetal health from maternal inflammation I 性干扰素通路。。GPRER1。。
  4. Plant roots sense soil compaction through restricted ethylene diffusion 土壤板结,不通气,乙烯聚集,抑制根部生长
  5. Driving energetically unfavorable dehydrogenation dynamics with plasmonics 水往高处流,啊不,是化学反应。。
  6. Learning the language of viral evolution and escape NLP,病毒逃逸免疫,改变特征但功能不变。。就像语言改变意思而语法不变
  7. Three-quarters attack rate of SARS-CoV-2 in the Brazilian Amazon during a largely unmitigated epidemic 亚马逊省的首府,44% 有新冠抗体,估计 76% 的人都感染了(2020年十月) “教科书式的群体免疫”
  8. Local convergence of behavior across species 局部环境,在不同物种间选择相似的行为
  9. Topological pumping of a 1D dipolar gas into strongly correlated prethermal states
  10. Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81 3.8 Å
  11. Structure of a transcribing RNA polymerase II–U1 snRNP complex 冷冻电镜,与转录同时发生的剪接


  1. Rapid spectral variability of a giant flare from a magnetar in NGC 253 磁星发出大耀斑,之前只有三个,且相机过曝;理论认为属于γ爆。作者,一个γ爆的X-射线和γ-射线观测数据,认为是磁星产生的。
  2. A bright γ-ray flare interpreted as a giant magnetar flare in NGC 253 同上,明确说了 GRB 200415A NGC 253 中的磁星产生的大耀斑
  3. An integrated space-to-ground quantum communication network over 4,600 kilometres 量子密钥分发,Quantum repeaters,地面线路+人造卫星
  4. Entangling logical qubits with lattice surgery 量子纠错,栅格
  5. Landau quantization and highly mobile fermions in an insulator 实验确认了 charge-neutral fermion 的存在
  6. Giant nonlinear optical responses from photon-avalanching nanoparticles 从 bulk materials 到 single nanostructures
  7. Antarctic icebergs reorganize ocean circulation during Pleistocene glacials 。。的原因不清楚,作者认为是。。冰山融化 -> 。。淡水重分配
  8. Functional adaptive landscapes predict terrestrial capacity at the origin of limbs 四足类登陆,完整化石太少,作者用 40 残肢化石。。发现 transitional..origin..adaptive
  9. Patterns of de novo tandem repeat mutations and their role in autism 基因组,de novo 串联重复,自闭症
  10. Sixteen facial expressions occur in similar contexts worldwide 146国家,6百万 video,上千种场景。。用深度学习分析人的面部表情的共性
  11. Distinct hypothalamic control of same- and opposite-sex mounting behaviour in mice 相同的行为、但内在目的不一样;作者与特定神经元联系起来
  12. Reconstitution of the oocyte transcriptional network with transcription factors 从多能干细胞到卵细胞,你只差 8 转录因子
  13. Identification of SARS-CoV-2 inhibitors using lung and colonic organoids 类器官,筛新冠药物
  14. A pooled testing strategy for identifying SARS-CoV-2 at low prevalence 新冠检测,合并样本,group size 要综合权衡多方因素
  15. Decoding myofibroblast origins in human kidney fibrosis 单细胞测序,一堆分析,检测,肾纤维化
  16. ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies 动脉粥样硬化,自身免疫,单细胞测序,发现 ALDH4A1 是抗原
  17. H1 histones control the epigenetic landscape by local chromatin compaction 敲除组蛋白 H1,染色质 compaction, Hi-C
  18. Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture 组蛋白 H1 是抑癌基因,淋巴瘤
  19. Structure and function of virion RNA polymerase of a crAss-like phage 一个蛋白质,发现是 RNA 聚合酶,X-ray 解结构。。。。认为真核生物的 RNA interference 聚合酶来自 噬菌体??
  20. Ultrafast structural changes within a photosynthetic reaction centre X-ray free-electron laser 看光合作用复合体的结构变化